Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1

Spinocerebellar ataxia type 1 (SCA1) is an intractable progressive neurodegenerative disease that leads to a range of movement and motor defects and is eventually lethal. Purkinje cells (PC) are typically the first to show signs of degeneration. SCA1 is caused by an expansion of the polyglutamine tr...

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Detalles Bibliográficos
Autores principales: Shuvaev, Anton N., Belozor, Olga S., Mozhei, Oleg I., Shuvaev, Andrey N., Fritsler, Yana V., Khilazheva, Elena D., Mosyagina, Angelina I., Hirai, Hirokazu, Teschemacher, Anja G., Kasparov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317252/
https://www.ncbi.nlm.nih.gov/pubmed/35883691
http://dx.doi.org/10.3390/cells11142247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317252/
https://www.ncbi.nlm.nih.gov/pubmed/35883691
http://dx.doi.org/10.3390/cells11142247

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