miR-143-3p Inhibits Aberrant Tau Phosphorylation and Amyloidogenic Processing of APP by Directly Targeting DAPK1 in Alzheimer’s Disease

The neuropathology of Alzheimer’s disease (AD) is characterized by intracellular aggregation of hyperphosphorylated tau and extracellular accumulation of beta-amyloid (Aβ). Death-associated protein kinase 1 (DAPK1), as a novel therapeutic target, shows promise for the treatment of human AD, but the...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Long, Shui, Xindong, Mei, Yingxue, Xia, Yongfang, Lan, Guihua, Hu, Li, Zhang, Mi, Gan, Chen-Ling, Li, Ruomeng, Tian, Yuan, Wang, Quling, Gu, Xi, Chen, Dongmei, Zhang, Tao, Lee, Tae Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317260/
https://www.ncbi.nlm.nih.gov/pubmed/35887339
http://dx.doi.org/10.3390/ijms23147992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317260/
https://www.ncbi.nlm.nih.gov/pubmed/35887339
http://dx.doi.org/10.3390/ijms23147992

Ejemplares similares