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Tropism of the Novel AAVBR1 Capsid Following Subretinal Delivery

A serious limitation of current adeno-associated viral (AAV) capsids employed for subretinal delivery is achieving adequate lateral spread beyond the injection site, required for the efficient delivery of gene therapy to the outer retina and/or RPE. AAVBR1 is a unique AAV with exceptional tropism fo...

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Detalles Bibliográficos
Autores principales: Carroll, Lara, Uehara, Hironori, Zhang, Xiaohui, Ambati, Balamurali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317317/
https://www.ncbi.nlm.nih.gov/pubmed/35887086
http://dx.doi.org/10.3390/ijms23147738