Cargando…
Tropism of the Novel AAVBR1 Capsid Following Subretinal Delivery
A serious limitation of current adeno-associated viral (AAV) capsids employed for subretinal delivery is achieving adequate lateral spread beyond the injection site, required for the efficient delivery of gene therapy to the outer retina and/or RPE. AAVBR1 is a unique AAV with exceptional tropism fo...
Autores principales: | Carroll, Lara, Uehara, Hironori, Zhang, Xiaohui, Ambati, Balamurali |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317317/ https://www.ncbi.nlm.nih.gov/pubmed/35887086 http://dx.doi.org/10.3390/ijms23147738 |
Ejemplares similares
-
RNA activating-double stranded RNA targeting flt-1 promoter inhibits endothelial cell proliferation through soluble FLT-1 upregulation
por: Choi, Susie, et al.
Publicado: (2018) -
Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide
por: Uehara, Hironori, et al.
Publicado: (2017) -
Systemic AAV10.COMP-Ang1 rescues renal glomeruli and pancreatic islets in type 2 diabetic mice
por: Tian, Mi, et al.
Publicado: (2020) -
The hunt for novel AAV capsids with improved cardiac tropism
por: Miguel-dos-Santos, Rodrigo, et al.
Publicado: (2023) -
Tropisms of AAV for Subretinal Delivery to the Neonatal Mouse Retina and Its Application for In Vivo Rescue of Developmental Photoreceptor Disorders
por: Watanabe, Satoshi, et al.
Publicado: (2013)