Design and Synthesis of Hepatitis B Virus (HBV) Capsid Assembly Modulators and Evaluation of Their Activity in Mammalian Cell Model

Capsid assembly modulators (CAMs) have emerged as a promising class of antiviral agents. We studied the effects of twenty-one newly designed and synthesized CAMs including heteroaryldihydropyrimidine compounds (HAPs), their analogs and standard compounds on hepatitis B virus (HBV) capsid assembly. C...

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Detalles Bibliográficos
Autores principales: Spunde, Karina, Vigante, Brigita, Dubova, Unda Nelda, Sipola, Anda, Timofejeva, Irena, Zajakina, Anna, Jansons, Juris, Plotniece, Aiva, Pajuste, Karlis, Sobolev, Arkadij, Muhamadejev, Ruslan, Jaudzems, Kristaps, Duburs, Gunars, Kozlovska, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317397/
https://www.ncbi.nlm.nih.gov/pubmed/35890072
http://dx.doi.org/10.3390/ph15070773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317397/
https://www.ncbi.nlm.nih.gov/pubmed/35890072
http://dx.doi.org/10.3390/ph15070773

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