Design and Synthesis of New Hydantoin Acetanilide Derivatives as Anti-NSCLC Targeting EGFR(L858R/T790M) Mutations

Epidermal Growth Factor Receptor (EGFR), its wild type and mutations L858R/T790M, is overexpressed in non-small cell lung cancer (NSCLC) patients and is considered an inevitable oncology target. However, while the potential EGFR inhibitors have been represented in the literature, their cellular acti...

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Detalles Bibliográficos
Autores principales: Hassanin, Moamen A., Mustafa, Muhamad, Abourehab, Mohammed A. S., Hassan, Heba A., Aly, Omar M., Beshr, Eman A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317481/
https://www.ncbi.nlm.nih.gov/pubmed/35890154
http://dx.doi.org/10.3390/ph15070857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317481/
https://www.ncbi.nlm.nih.gov/pubmed/35890154
http://dx.doi.org/10.3390/ph15070857

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