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Induced Endothelial Cell-Integrated Liver Assembloids Promote Hepatic Maturation and Therapeutic Effect on Cholestatic Liver Fibrosis

The transplantation of pluripotent stem cell (PSC)-derived liver organoids has been studied to solve the current donor shortage. However, the differentiation of unintended cell populations, difficulty in generating multi-lineage organoids, and tumorigenicity of PSC-derived organoids are challenges....

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Detalles Bibliográficos
Autores principales: Nam, Donggyu, Park, Myung Rae, Lee, Hyunah, Bae, Sung Chul, Gerovska, Daniela, Araúzo-Bravo, Marcos J., Zaehres, Holm, Schöler, Hans R., Kim, Jeong Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317515/
https://www.ncbi.nlm.nih.gov/pubmed/35883684
http://dx.doi.org/10.3390/cells11142242