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Proteomic Investigation of the Role of Nucleostemin in Nucleophosmin-Mutated OCI-AML 3 Cell Line

Nucleostemin (NS; a product of the GNL3 gene) is a nucleolar–nucleoplasm shuttling GTPase whose levels are high in stem cells and rapidly decrease upon differentiation. NS levels are also high in several solid and hematological neoplasms, including acute myeloid leukaemia (AML). While a role in telo...

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Detalles Bibliográficos
Autores principales: Cela, Ilaria, Cufaro, Maria Concetta, Fucito, Maurine, Pieragostino, Damiana, Lanuti, Paola, Sallese, Michele, Del Boccio, Piero, Di Matteo, Adele, Allocati, Nerino, De Laurenzi, Vincenzo, Federici, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317519/
https://www.ncbi.nlm.nih.gov/pubmed/35886999
http://dx.doi.org/10.3390/ijms23147655