Microbial Metabolite 3-Indolepropionic Acid Mediates Immunosuppression

The microbial-derived metabolite, 3-indolepropionic acid (3-IPA), has been intensely studied since its origins were discovered in 2009; however, 3-IPA’s role in immunosuppression has had limited attention. Untargeted metabolomic analyses of T-cell exhaustion and immunosuppression, represented by dys...

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Detalles Bibliográficos
Autores principales: Guijas, Carlos, Horton, Lucy E., Hoang, Linh, Domingo-Almenara, Xavier, Billings, Elizabeth M., Ware, Brian C., Sullivan, Brian, Siuzdak, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317520/
https://www.ncbi.nlm.nih.gov/pubmed/35888769
http://dx.doi.org/10.3390/metabo12070645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317520/
https://www.ncbi.nlm.nih.gov/pubmed/35888769
http://dx.doi.org/10.3390/metabo12070645

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