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Microbial Metabolite 3-Indolepropionic Acid Mediates Immunosuppression
The microbial-derived metabolite, 3-indolepropionic acid (3-IPA), has been intensely studied since its origins were discovered in 2009; however, 3-IPA’s role in immunosuppression has had limited attention. Untargeted metabolomic analyses of T-cell exhaustion and immunosuppression, represented by dys...
Autores principales: | Guijas, Carlos, Horton, Lucy E., Hoang, Linh, Domingo-Almenara, Xavier, Billings, Elizabeth M., Ware, Brian C., Sullivan, Brian, Siuzdak, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317520/ https://www.ncbi.nlm.nih.gov/pubmed/35888769 http://dx.doi.org/10.3390/metabo12070645 |
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