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Hydrophilic But Not Hydrophobic Surfactant Protein Genetic Variants Are Associated With Severe Acute Respiratory Syncytial Virus Infection in Children

Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection-related hospitalization in the first year of life. Surfactant dysfunction is central to pathophysiologic mechanisms of various pulmonary diseases including RSV. We hypothesized that RSV severity is associated...

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Detalles Bibliográficos
Autores principales: Depicolzuane, Lynnlee C., Roberts, Catherine M., Thomas, Neal J., Anderson-Fears, Keenan, Liu, Dajiang, Barbosa, João Paulo Pereira, Souza, Felipe Rodrigues, Pimentel, André Silva, Floros, Joanna, Gandhi, Chintan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317530/
https://www.ncbi.nlm.nih.gov/pubmed/35903101
http://dx.doi.org/10.3389/fimmu.2022.922956