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Two Novel Co-Crystals of Naproxen: Comparison of Stability, Solubility and Intermolecular Interaction

Two novel co-crystals of naproxen (NPX) were designed and prepared at a stoichiometric ratio of 1:1, namely, naproxen–caprolactam (NPX–CPL) and naproxen–oxymatrine (NPX–OMT). The characteristics of the co-crystals were evaluated in terms of stability and solubility studies. In terms of solubility, i...

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Detalles Bibliográficos
Autores principales: Xing, Cheng, Chen, Ting, Wang, Li, An, Qi, Jin, Yali, Yang, Dezhi, Zhang, Li, Du, Guanhua, Lu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317554/
https://www.ncbi.nlm.nih.gov/pubmed/35890107
http://dx.doi.org/10.3390/ph15070807