Updates in the Use of BCL-2-Family Small Molecule Inhibitors for the Treatment of Relapsed/Refractory Multiple Myeloma

SIMPLE SUMMARY: Monumental therapeutic advances have been made over the past two decades for the treatment of multiple myeloma. Anti-apoptotic proteins, such as Bcl-2, Bcl-xL, and Mcl-1, have been found to be upregulated in multiple myeloma cell lines, and small molecule inhibitors that target these...

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Detalles Bibliográficos
Autores principales: Parrondo, Ricardo D., Paulus, Aneel, Ailawadhi, Sikander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317574/
https://www.ncbi.nlm.nih.gov/pubmed/35884390
http://dx.doi.org/10.3390/cancers14143330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317574/
https://www.ncbi.nlm.nih.gov/pubmed/35884390
http://dx.doi.org/10.3390/cancers14143330

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