Glycyrrhizic Acid Attenuates Pulmonary Fibrosis of Silicosis by Inhibiting the Interaction between HMGB1 and BRG1 through PI3K/Akt/mTOR Pathway

Purpose: High mobility group protein 1 (HMGB1) is a highly conserved DNA-binding nuclear protein that participates in the occurrence and development of silicosis. HMGB1 binds to its specific receptor and activates phosphatidylinositol 3-kinase (PI3K)/protein kinase B, (PKB; Akt)/mammalian target of...

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Detalles Bibliográficos
Autores principales: Niu, Zhuoya, Lin, Jisong, Hao, Changfu, Xu, Xiao, Wang, Chen, Dai, Kai, Deng, Xuedan, Deng, Meng, Guo, Yonghua, Yao, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317839/
https://www.ncbi.nlm.nih.gov/pubmed/35886594
http://dx.doi.org/10.3390/ijerph19148743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317839/
https://www.ncbi.nlm.nih.gov/pubmed/35886594
http://dx.doi.org/10.3390/ijerph19148743

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