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Preparation of Deuterium-Labeled Armodafinil by Hydrogen–Deuterium Exchange and Its Application in Quantitative Analysis by LC-MS

Armodafinil, the R enantiomer of modafinil, was approved in 2007 by the US Food and Drug Administration as a wake-promoting agent for excessive sleepiness treatment. Due to its abuse by students and athletes, there is a need of its quantification. Quantitative analysis by liquid chromatography-mass...

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Detalles Bibliográficos
Autores principales: Grocholska, Paulina, Wieczorek, Robert, Bąchor, Remigiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317911/
https://www.ncbi.nlm.nih.gov/pubmed/35888702
http://dx.doi.org/10.3390/metabo12070578