Co-Combination of Pregabalin and Withania coagulans-Extract-Loaded Topical Gel Alleviates Allodynia and Hyperalgesia in the Chronic Sciatic Nerve Constriction Injury for Neuropathic Pain in Animal Model

The current study reports the fabrication of co-combination gel using Pregabalin and Withania coagulans fruit extract to validate its effectiveness for neuropathic pain in chronic constriction injury (CCI) rat models. Three topical gels were prepared using Carbopol 934 through a pseudo-ternary phase...

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Detalles Bibliográficos
Autores principales: Asghar, Anam, Aamir, Muhammad Naeem, Sheikh, Fatima Akbar, Ahmad, Naveed, Elsherif, Mervat A., Abbas Bukhari, Syed Nasir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317976/
https://www.ncbi.nlm.nih.gov/pubmed/35889307
http://dx.doi.org/10.3390/molecules27144433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317976/
https://www.ncbi.nlm.nih.gov/pubmed/35889307
http://dx.doi.org/10.3390/molecules27144433

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