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Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction

Plastoquinone analogs are privileged structures among the known antiproliferative natural product-based compound families. Exploiting one of these analogs as a lead structure, we report the investigation of the brominated PQ analogs (BrPQ) in collaboration with the National Cancer Institute of Bethe...

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Detalles Bibliográficos
Autores principales: Jannuzzi, Ayse Tarbin, Yilmaz Goler, Ayse Mine, Bayrak, Nilüfer, Yıldız, Mahmut, Yıldırım, Hatice, Karademir Yilmaz, Betul, Shilkar, Deepak, Venkatesan, Raghusrinivasan Jayaprakash, Jayaprakash, Venkatesan, TuYuN, Amaç Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318129/
https://www.ncbi.nlm.nih.gov/pubmed/35890076
http://dx.doi.org/10.3390/ph15070777