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Improved Therapy of B-Cell Non-Hodgkin Lymphoma by Obinutuzumab-Dianthin Conjugates in Combination with the Endosomal Escape Enhancer SO1861

Immunotoxins do not only bind to cancer-specific receptors to mediate the elimination of tumor cells through the innate immune system, but also increase target cytotoxicity by the intrinsic toxin activity. The plant glycoside SO1861 was previously reported to enhance the endolysosomal escape of anti...

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Detalles Bibliográficos
Autores principales: Panjideh, Hossein, Niesler, Nicole, Weng, Alexander, Fuchs, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318199/
https://www.ncbi.nlm.nih.gov/pubmed/35878216
http://dx.doi.org/10.3390/toxins14070478