A Novel ALDH1A1 Inhibitor Blocks Platinum-Induced Senescence and Stemness in Ovarian Cancer

SIMPLE SUMMARY: Ovarian cancer is the deadliest amongst the gynecologic malignancies. Most ovarian cancer patients initially respond to chemotherapy but will eventually relapse and become chemoresistant. A specialized subpopulation of cells within the tumor known as cancer stem cells are known to co...

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Detalles Bibliográficos
Autores principales: Muralikrishnan, Vaishnavi, Fang, Fang, Given, Tyler C., Podicheti, Ram, Chtcherbinine, Mikhail, Metcalfe, Tara X., Sriramkumar, Shruthi, O’Hagan, Heather M., Hurley, Thomas D., Nephew, Kenneth P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318275/
https://www.ncbi.nlm.nih.gov/pubmed/35884498
http://dx.doi.org/10.3390/cancers14143437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318275/
https://www.ncbi.nlm.nih.gov/pubmed/35884498
http://dx.doi.org/10.3390/cancers14143437

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