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A Novel ALDH1A1 Inhibitor Blocks Platinum-Induced Senescence and Stemness in Ovarian Cancer
SIMPLE SUMMARY: Ovarian cancer is the deadliest amongst the gynecologic malignancies. Most ovarian cancer patients initially respond to chemotherapy but will eventually relapse and become chemoresistant. A specialized subpopulation of cells within the tumor known as cancer stem cells are known to co...
Autores principales: | Muralikrishnan, Vaishnavi, Fang, Fang, Given, Tyler C., Podicheti, Ram, Chtcherbinine, Mikhail, Metcalfe, Tara X., Sriramkumar, Shruthi, O’Hagan, Heather M., Hurley, Thomas D., Nephew, Kenneth P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318275/ https://www.ncbi.nlm.nih.gov/pubmed/35884498 http://dx.doi.org/10.3390/cancers14143437 |
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