Amorphigenin from Amorpha fruticosa L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent- and AMPK-Dependent Manner

In this study, we investigated the depigmentation effect of Amorpha fruticosa L. root extract (RE), an herbal medicine. A. fruticosa RE significantly induced depigmentation in α-MSH-treated B16F10 cells at noncytotoxic concentrations. Further, the RE decreased the protein levels of the melanosomal p...

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Detalles Bibliográficos
Autores principales: Lee, Ki Won, Nguyen, Dang Thi, Kim, Minju, Lee, Si Hyeon, Lim, Seyeon, Kim, Jisu, Park, Ki Hun, Kim, Jeong Yoon, Yoo, Jiyun, Hwangbo, Cheol, Kim, Kwang Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318381/
https://www.ncbi.nlm.nih.gov/pubmed/35877420
http://dx.doi.org/10.3390/cimb44070196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318381/
https://www.ncbi.nlm.nih.gov/pubmed/35877420
http://dx.doi.org/10.3390/cimb44070196

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