Cargando…

Amorphigenin from Amorpha fruticosa L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent- and AMPK-Dependent Manner

In this study, we investigated the depigmentation effect of Amorpha fruticosa L. root extract (RE), an herbal medicine. A. fruticosa RE significantly induced depigmentation in α-MSH-treated B16F10 cells at noncytotoxic concentrations. Further, the RE decreased the protein levels of the melanosomal p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Ki Won, Nguyen, Dang Thi, Kim, Minju, Lee, Si Hyeon, Lim, Seyeon, Kim, Jisu, Park, Ki Hun, Kim, Jeong Yoon, Yoo, Jiyun, Hwangbo, Cheol, Kim, Kwang Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318381/ https://www.ncbi.nlm.nih.gov/pubmed/35877420 http://dx.doi.org/10.3390/cimb44070196

Ejemplares similares

Toxicity of Amorphigenin from the Seeds of Amorpha fruticosa against the Larvae of Culex pipiens pallens (Diptera: Culicidae)
por: Liang, Yaping, et al.
Publicado: (2015)

New Class of Tyrosinase Inhibitors, Rotenoids, from Amorpha fruticosa
por: Moon, Si Won, et al.
Publicado: (2023)

Tyrosinase Inhibition and Kinetic Details of Puerol A Having But-2-Enolide Structure from Amorpha fruticosa
por: Kim, Jeong Ho, et al.
Publicado: (2020)

Proteomic analysis of symbiotic proteins of Glomus mosseae and Amorpha fruticosa
por: Song, Fuqiang, et al.
Publicado: (2015)

Analysis of bioactive constituents from the leaves of Amorpha fruticosa L
por: Cui, Xueqin, et al.
Publicado: (2016)

Antioxidant and acetylcholinesterase inhibition properties of Amorpha fruticosa L. and Phytolacca americana L.
por: Zheleva-Dimitrova, Dimitrina Zh.
Publicado: (2013)

Functional Study of Amorpha fruticosa WRKY20 Gene in Response to Drought Stress
por: Li, Danni, et al.
Publicado: (2023)

Drought resistance of tobacco overexpressing the AfNAC1 gene of Amorpha fruticosa Linn.
por: Li, Minghui, et al.
Publicado: (2022)

Phytostabilization of Pb-Zn Mine Tailings with Amorpha fruticosa Aided by Organic Amendments and Triple Superphosphate
por: Sikdar, Ashim, et al.
Publicado: (2020)

Chemical Composition, Antipathogenic and Cytotoxic Activity of the Essential Oil Extracted from Amorpha fruticosa Fruits
por: Marinas, Ioana Cristina, et al.
Publicado: (2021)

Study on the cohesive shear characteristics and intrinsic modelling of the root–tailing soil interface of Amorpha fruticosa
por: Yang, Qing Chao, et al.
Publicado: (2022)

Sap flow of Amorpha fruticosa: implications of water use strategy in a semiarid system with secondary salinization
por: Cao, Qiqi, et al.
Publicado: (2020)

A Novel Chinese Honey from Amorpha fruticosa L.: Nutritional Composition and Antioxidant Capacity In Vitro
por: Zhu, Min, et al.
Publicado: (2020)

A review on invasive false indigo bush (Amorpha fruticosa L.): Nuisance plant with multiple benefits
por: Grabić, Jasna, et al.
Publicado: (2022)

Amorpha fruticosa – A Noxious Invasive Alien Plant in Europe or a Medicinal Plant against Metabolic Disease?
por: Kozuharova, Ekaterina, et al.
Publicado: (2017)

De novo assembly of Amorpha fruticosa L. transcriptome in response to drought stress provides insight into the tolerance mechanisms
por: Sun, Xinzhu, et al.
Publicado: (2021)

Contrasting dynamics of leaf potential and gas exchange during progressive drought cycles and recovery in Amorpha fruticosa and Robinia pseudoacacia
por: Yan, Weiming, et al.
Publicado: (2017)

A Study on the Safety and Effects of Amorpha fruticosa Fruit Extract on Spontaneously Hypertensive Rats with Induced Type 2 Diabetes
por: Simeonova, Rumyana, et al.
Publicado: (2022)

Amorphigenin inhibits Osteoclast differentiation by suppressing c-Fos and nuclear factor of activated T cells
por: Kim, Bong Gyu, et al.
Publicado: (2010)

AMPK–mTOR Signaling and Cellular Adaptations in Hypoxia
por: Chun, Yoomi, et al.
Publicado: (2021)

Improvement of growth performance of Amorpha fruticosa under contrasting regime of water and fertilizer in coal-contaminated spoils using response surface methodology
por: Roy, Rana, et al.
Publicado: (2020)

Ethanol extract of Remotiflori radix induces endoplasmic reticulum stress-mediated cell death through AMPK/mTOR signaling in human prostate cancer cells
por: Kim, Aeyung, et al.
Publicado: (2015)

Headspace, Volatile and Semi-Volatile Organic Compounds Diversity and Radical Scavenging Activity of Ultrasonic Solvent Extracts from Amorpha fruticosa Honey Samples
por: Jerković, Igor, et al.
Publicado: (2009)

Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells
por: Zhu, Xiaohui, et al.
Publicado: (2017)

Chelidonine Induces Caspase-Dependent and Caspase-Independent Cell Death through G(2/M) Arrest in the T98G Human Glioblastoma Cell Line
por: Lee, Yeon-Kyeong, et al.
Publicado: (2019)

Effect of Arbuscular Mycorrhiza Fungus Diversispora eburnea Inoculation on Lolium perenne and Amorpha fruticosa Growth, Cadmium Uptake, and Soil Cadmium Speciation in Cadmium-Contaminated Soil
por: Sun, Jiahua, et al.
Publicado: (2023)

Silencing of Twist1 sensitizes NSCLC cells to cisplatin via AMPK-activated mTOR inhibition
por: Jin, H-O, et al.
Publicado: (2012)

Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1–AMPK–mTOR axis
por: Jung, Taek-Yeol, et al.
Publicado: (2020)

Inhibitory Effects of Amorphigenin on the Mitochondrial Complex I of Culex pipiens pallens Coquillett (Diptera: Culicidae)
por: Ji, Mingshan, et al.
Publicado: (2015)

Quercetin Regulates Sestrin 2-AMPK-mTOR Signaling Pathway and Induces Apoptosis via Increased Intracellular ROS in HCT116 Colon Cancer Cells
por: Kim, Guen Tae, et al.
Publicado: (2013)

The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner
por: Zhang, Ying, et al.
Publicado: (2021)

Central Exercise Action Increases the AMPK and mTOR Response to Leptin
por: Ropelle, Eduardo R., et al.
Publicado: (2008)

TFEC contributes to cardiac hypertrophy by inhibiting AMPK/mTOR signaling
por: Zhao, Ting, et al.
Publicado: (2021)

Sinensetin Induces Autophagic Cell Death through p53-Related AMPK/mTOR Signaling in Hepatocellular Carcinoma HepG2 Cells
por: Kim, Seong Min, et al.
Publicado: (2020)

Strategies of Eradicating Glioma Cells: A Multi-Scale Mathematical Model with MiR-451-AMPK-mTOR Control
por: Kim, Yangjin, et al.
Publicado: (2015)

Neuroprotective effects of osmotin in Parkinson’s disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways
por: Park, Jun Sung, et al.
Publicado: (2023)

Whitening effect of novel peptide mixture by regulating melanosome biogenesis, transfer and degradation
por: Lee, Eung-Ji, et al.
Publicado: (2021)

The Effects of Exogenous Lactate Administration on the IGF1/Akt/mTOR Pathway in Rat Skeletal Muscle
por: Kyun, Sunghwan, et al.
Publicado: (2020)

Hesperidin Suppresses Melanosome Transport by Blocking the Interaction of Rab27A-Melanophilin
por: Kim, Bora, et al.
Publicado: (2013)

A Simple Assay Method for Melanosome Transfer
por: Choi, Hye Ryung, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_08hbsq1ljvusprv9setcq1sq1p