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TAaCGH Suite for Detecting Cancer—Specific Copy Number Changes Using Topological Signatures
Copy number changes play an important role in the development of cancer and are commonly associated with changes in gene expression. Persistence curves, such as Betti curves, have been used to detect copy number changes; however, it is known these curves are unstable with respect to small perturbati...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318413/ https://www.ncbi.nlm.nih.gov/pubmed/35885119 http://dx.doi.org/10.3390/e24070896 |