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TAaCGH Suite for Detecting Cancer—Specific Copy Number Changes Using Topological Signatures

Copy number changes play an important role in the development of cancer and are commonly associated with changes in gene expression. Persistence curves, such as Betti curves, have been used to detect copy number changes; however, it is known these curves are unstable with respect to small perturbati...

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Detalles Bibliográficos
Autores principales: Aslam, Jai, Ardanza-Trevijano, Sergio, Xiong, Jingwei, Arsuaga, Javier, Sazdanovic, Radmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318413/
https://www.ncbi.nlm.nih.gov/pubmed/35885119
http://dx.doi.org/10.3390/e24070896