The Cholesterol-Modulating Effect of the New Herbal Medicinal Recipe from Yellow Vine (Coscinium fenestratum (Goetgh.)), Ginger (Zingiber officinale Roscoe.), and Safflower (Carthamus tinctorius L.) on Suppressing PCSK9 Expression to Upregulate LDLR Expression in HepG2 Cells

PCSK9 is a promising target for developing novel cholesterol-lowering drugs. We developed a recipe that combined molecular docking, GC-MS/MS, and real-time PCR to identify potential PCSK9 inhibitors for herb ratio determination. Three herbs, Carthamus tinctorius, Coscinium fenestratum, and Zingiber...

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Detalles Bibliográficos
Autores principales: Ongtanasup, Tassanee, Prommee, Nuntika, Jampa, Onkamon, Limcharoen, Thanchanok, Wanmasae, Smith, Nissapatorn, Veeranoot, Paul, Alok K., Pereira, Maria de Lourdes, Wilairatana, Polrat, Nasongkla, Norased, Eawsakul, Komgrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318486/
https://www.ncbi.nlm.nih.gov/pubmed/35890469
http://dx.doi.org/10.3390/plants11141835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318486/
https://www.ncbi.nlm.nih.gov/pubmed/35890469
http://dx.doi.org/10.3390/plants11141835

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