Critical Quality Control Methods for a Novel Anticoagulant Candidate LFG-Na by HPSEC-MALLS-RID and Bioactivity Assays

A low molecular weight fucosylated glycosaminoglycan sodium (LFG-Na) is a novel anticoagulant candidate from the sea cucumber Holothuria fuscopunctata that selectively inhibits intrinsic tenase (iXase). The molecular weight, molecular weight distribution and bioactivities are the critical quality at...

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Detalles Bibliográficos
Autores principales: Zheng, Shunliang, Wang, Yi, Wu, Jiashuo, Wang, Siyao, Wei, Huaifu, Zhang, Yongchun, Zhou, Jianbo, Shi, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318522/
https://www.ncbi.nlm.nih.gov/pubmed/35889395
http://dx.doi.org/10.3390/molecules27144522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318522/
https://www.ncbi.nlm.nih.gov/pubmed/35889395
http://dx.doi.org/10.3390/molecules27144522

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