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The Role of the Na(+)/Ca(2+) Exchanger in Aberrant Intracellular Ca(2+) in Cardiomyocytes of Chagas-Infected Rodents

Chagas disease is produced by the parasite Trypanosoma cruzi (T. cruzi), which is the leading cause of death and morbidity in Latin America. We have shown that in patients with Chagas cardiomyopathy, there is a chronic elevation of diastolic Ca(2+) concentration ([Ca(2+)](d)), associated with deteri...

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Detalles Bibliográficos
Autores principales: Lopez, Jose R., Linares, Nancy, Adams, Jose A., Mijares, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318578/
https://www.ncbi.nlm.nih.gov/pubmed/35903196
http://dx.doi.org/10.3389/fcimb.2022.890709