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ATP13A2 Declines Zinc-Induced Accumulation of α-Synuclein in a Parkinson’s Disease Model

Parkinson’s disease (PD) is characterized by the presence of Lewy bodies caused by α-synuclein. The imbalance of zinc homeostasis is a major cause of PD, promoting α-synuclein accumulation. ATP13A2, a transporter found in acidic vesicles, plays an important role in Zn(2+) homeostasis and is highly e...

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Detalles Bibliográficos
Autores principales: Gao, Huiling, Sun, Hehong, Yan, Nan, Zhao, Pu, Xu, He, Zheng, Wei, Zhang, Xiaoyu, Wang, Tao, Guo, Chuang, Zhong, Manli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318580/
https://www.ncbi.nlm.nih.gov/pubmed/35887392
http://dx.doi.org/10.3390/ijms23148035