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ATP13A2 Declines Zinc-Induced Accumulation of α-Synuclein in a Parkinson’s Disease Model
Parkinson’s disease (PD) is characterized by the presence of Lewy bodies caused by α-synuclein. The imbalance of zinc homeostasis is a major cause of PD, promoting α-synuclein accumulation. ATP13A2, a transporter found in acidic vesicles, plays an important role in Zn(2+) homeostasis and is highly e...
Autores principales: | Gao, Huiling, Sun, Hehong, Yan, Nan, Zhao, Pu, Xu, He, Zheng, Wei, Zhang, Xiaoyu, Wang, Tao, Guo, Chuang, Zhong, Manli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318580/ https://www.ncbi.nlm.nih.gov/pubmed/35887392 http://dx.doi.org/10.3390/ijms23148035 |
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