Effects of TP53 Mutations and miRs on Immune Responses in the Tumor Microenvironment Important in Pancreatic Cancer Progression

Approximately 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC). PDAC is the fourth leading cause of cancer death world-wide. Therapies for PDAC are largely ineffective due to the dense desmoplastic tumor microenvironment which prevents chemotherapeutic drugs and small molecule...

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Detalles Bibliográficos
Autores principales: McCubrey, James A., Yang, Li V., Abrams, Stephen L., Steelman, Linda S., Follo, Matilde Y., Cocco, Lucio, Ratti, Stefano, Martelli, Alberto M., Augello, Giuseppa, Cervello, Melchiorre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318640/
https://www.ncbi.nlm.nih.gov/pubmed/35883598
http://dx.doi.org/10.3390/cells11142155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318640/
https://www.ncbi.nlm.nih.gov/pubmed/35883598
http://dx.doi.org/10.3390/cells11142155

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