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Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions

Toll-interleukin receptor (TIR) domains have emerged as critical players involved in innate immune signaling in humans but are also expressed as potential virulence factors within multiple pathogenic bacteria. However, there has been a shortage of structural studies aimed at elucidating atomic resol...

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Detalles Bibliográficos
Autores principales: Lee, Eunjeong, Redzic, Jasmina S., Nemkov, Travis, Saviola, Anthony J., Dzieciatkowska, Monika, Hansen, Kirk C., D’Alessandro, Angelo, Dinarello, Charles, Eisenmesser, Elan Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318647/
https://www.ncbi.nlm.nih.gov/pubmed/35889366
http://dx.doi.org/10.3390/molecules27144494