Activation of Anti-SARS-CoV-2 Human CTLs by Extracellular Vesicles Engineered with the N Viral Protein

We propose an innovative anti-SARS-CoV-2 immune strategy based on extracellular vesicles (EVs) inducing an anti-SARS-CoV-2 N CD8(+) T cytotoxic lymphocyte (CTL) immune response. We previously reported that the SARS-CoV-2 N protein can be uploaded at high levels in EVs upon fusion with Nef(mut), i.e....

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Detalles Bibliográficos
Autores principales: Manfredi, Francesco, Chiozzini, Chiara, Ferrantelli, Flavia, Leone, Patrizia, Giovannelli, Andrea, Sanchez, Massimo, Federico, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318727/
https://www.ncbi.nlm.nih.gov/pubmed/35891224
http://dx.doi.org/10.3390/vaccines10071060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318727/
https://www.ncbi.nlm.nih.gov/pubmed/35891224
http://dx.doi.org/10.3390/vaccines10071060

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