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Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood–Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations

Liver injury is often associated with hepatic retinopathy, resulting from accumulation of retinal toxins due to blood–retinal barrier (BRB) dysfunction. Retinal pigment epithelium highly expresses MRP1/Mrp1. We aimed to investigate whether liver injury affects the function and expression of retinal...

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Detalles Bibliográficos
Autores principales: Li, Ping, Yang, Yiting, Lin, Zijin, Hong, Shijin, Jiang, Ling, Zhou, Han, Yang, Lu, Zhu, Liang, Liu, Xiaodong, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318728/
https://www.ncbi.nlm.nih.gov/pubmed/35887010
http://dx.doi.org/10.3390/ijms23147666