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Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood–Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations
Liver injury is often associated with hepatic retinopathy, resulting from accumulation of retinal toxins due to blood–retinal barrier (BRB) dysfunction. Retinal pigment epithelium highly expresses MRP1/Mrp1. We aimed to investigate whether liver injury affects the function and expression of retinal...
Autores principales: | Li, Ping, Yang, Yiting, Lin, Zijin, Hong, Shijin, Jiang, Ling, Zhou, Han, Yang, Lu, Zhu, Liang, Liu, Xiaodong, Liu, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318728/ https://www.ncbi.nlm.nih.gov/pubmed/35887010 http://dx.doi.org/10.3390/ijms23147666 |
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