Scorpion Peptide Smp24 Exhibits a Potent Antitumor Effect on Human Lung Cancer Cells by Damaging the Membrane and Cytoskeleton In Vivo and In Vitro

Smp24, a cationic antimicrobial peptide identified from the venom gland of the Egyptian scorpion Scorpio maurus palmatus, shows variable cytotoxicity on various tumor (KG1a, CCRF-CEM and HepG2) and non-tumor (CD34(+), HRECs, HACAT) cell lines. However, the effects of Smp24 and its mode of action on...

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Detalles Bibliográficos
Autores principales: Guo, Ruiyin, Liu, Junfang, Chai, Jinwei, Gao, Yahua, Abdel-Rahman, Mohamed A., Xu, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318729/
https://www.ncbi.nlm.nih.gov/pubmed/35878176
http://dx.doi.org/10.3390/toxins14070438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318729/
https://www.ncbi.nlm.nih.gov/pubmed/35878176
http://dx.doi.org/10.3390/toxins14070438

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