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Codelivery of HBx-siRNA and Plasmid Encoding IL-12 for Inhibition of Hepatitis B Virus and Reactivation of Antiviral Immunity

Chronic hepatitis B is a critical cause of many serious liver diseases such as hepatocellular carcinoma (HCC). The main challenges in hepatitis B treatment include the rebound of hepatitis B virus (HBV)-related antigen levels after drug withdrawal and the immunosuppression caused by the virus. Herei...

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Detalles Bibliográficos
Autores principales: Mu, Yan, Ren, Xiao-He, Han, Di, Guan, Ying-Ying, Liu, Pei-Ling, Cheng, Si-Xue, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318813/
https://www.ncbi.nlm.nih.gov/pubmed/35890334
http://dx.doi.org/10.3390/pharmaceutics14071439