Differential Effects of a Novel Opioid Ligand UTA1003 on Antinociceptive Tolerance and Motor Behaviour

Analgesic tolerance is a major problem in the clinic for the maintenance of opioid-induced long-term pain relief. Opioids with mixed activity on multiple opioid receptors promise reduced antinociceptive tolerance in preclinical studies, but these compounds typically show poor bioavailability upon or...

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Detalles Bibliográficos
Autores principales: Paul, Alok K., Woolley, Krystel L., Rahmatullah, Mohammed, Wilairatana, Polrat, Smith, Jason A., Gueven, Nuri, Dietis, Nikolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318816/
https://www.ncbi.nlm.nih.gov/pubmed/35890089
http://dx.doi.org/10.3390/ph15070789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318816/
https://www.ncbi.nlm.nih.gov/pubmed/35890089
http://dx.doi.org/10.3390/ph15070789

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