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HPLC-Based Purification and Isolation of Potent Anti-HIV and Latency Reversing Daphnane Diterpenes from the Medicinal Plant Gnidia sericocephala (Thymelaeaceae)

Despite the success of combination antiretroviral therapy (cART), HIV persists in low- and middle-income countries (LMIC) due to emerging drug resistance and insufficient drug accessibility. Furthermore, cART does not target latently-infected CD4+ T cells, which represent a major barrier to HIV erad...

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Detalles Bibliográficos
Autores principales: Tembeni, Babalwa, Sciorillo, Amanda, Invernizzi, Luke, Klimkait, Thomas, Urda, Lorena, Moyo, Phanankosi, Naidoo-Maharaj, Dashnie, Levitties, Nathan, Gyampoh, Kwasi, Zu, Guorui, Yuan, Zhe, Mounzer, Karam, Nkabinde, Siphathimandla, Nkabinde, Magugu, Gqaleni, Nceba, Tietjen, Ian, Montaner, Luis J., Maharaj, Vinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318819/
https://www.ncbi.nlm.nih.gov/pubmed/35891417
http://dx.doi.org/10.3390/v14071437