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HPLC-Based Purification and Isolation of Potent Anti-HIV and Latency Reversing Daphnane Diterpenes from the Medicinal Plant Gnidia sericocephala (Thymelaeaceae)
Despite the success of combination antiretroviral therapy (cART), HIV persists in low- and middle-income countries (LMIC) due to emerging drug resistance and insufficient drug accessibility. Furthermore, cART does not target latently-infected CD4+ T cells, which represent a major barrier to HIV erad...
Autores principales: | Tembeni, Babalwa, Sciorillo, Amanda, Invernizzi, Luke, Klimkait, Thomas, Urda, Lorena, Moyo, Phanankosi, Naidoo-Maharaj, Dashnie, Levitties, Nathan, Gyampoh, Kwasi, Zu, Guorui, Yuan, Zhe, Mounzer, Karam, Nkabinde, Siphathimandla, Nkabinde, Magugu, Gqaleni, Nceba, Tietjen, Ian, Montaner, Luis J., Maharaj, Vinesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318819/ https://www.ncbi.nlm.nih.gov/pubmed/35891417 http://dx.doi.org/10.3390/v14071437 |
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