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Cytotoxic Effects on Breast Cancer Cell Lines of Chalcones Derived from a Natural Precursor and Their Molecular Docking Analysis

This study aimed to determine the in vitro cytotoxicity and understand possible cytotoxic mechanisms via an in silico study of eleven chalcones synthesized from two acetophenones. Five were synthesized from a prenylacetophenone isolated from a plant that grows in the Andean region of the Atacama Des...

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Detalles Bibliográficos
Autores principales: Bustos, Luis, Echiburú-Chau, Carlos, Castro-Alvarez, Alejandro, Bradshaw, Ben, Simirgiotis, Mario J., Mellado, Marco, Parra, Claudio, Cuellar, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318862/
https://www.ncbi.nlm.nih.gov/pubmed/35889260
http://dx.doi.org/10.3390/molecules27144387