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Off-Target Effect of Activation of NF-κB by HIV Latency Reversal Agents on Transposable Elements Expression

Many drugs have been evaluated to reactivate HIV-1 from cellular reservoirs, but the off-target effects of these latency reversal agents (LRA) remain poorly defined. Transposable elements (TEs) are reactivated during HIV-1 infection, but studies of potential off-target drug effects on TE expression...

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Detalles Bibliográficos
Autores principales: Curty, Gislaine, Iniguez, Luis P., Soares, Marcelo A., Nixon, Douglas F., de Mulder Rougvie, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318874/
https://www.ncbi.nlm.nih.gov/pubmed/35891551
http://dx.doi.org/10.3390/v14071571