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Altered Balance of Reelin Proteolytic Fragments in the Cerebrospinal Fluid of Alzheimer’s Disease Patients

Reelin binds to the apolipoprotein E receptor apoER2 to activate an intracellular signaling cascade. The proteolytic cleavage of reelin follows receptor binding but can also occur independently of its binding to receptors. This study assesses whether reelin proteolytic fragments are differentially a...

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Detalles Bibliográficos
Autores principales: Lopez-Font, Inmaculada, Lennol, Matthew P., Iborra-Lazaro, Guillermo, Zetterberg, Henrik, Blennow, Kaj, Sáez-Valero, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318932/
https://www.ncbi.nlm.nih.gov/pubmed/35886870
http://dx.doi.org/10.3390/ijms23147522