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Altered Balance of Reelin Proteolytic Fragments in the Cerebrospinal Fluid of Alzheimer’s Disease Patients
Reelin binds to the apolipoprotein E receptor apoER2 to activate an intracellular signaling cascade. The proteolytic cleavage of reelin follows receptor binding but can also occur independently of its binding to receptors. This study assesses whether reelin proteolytic fragments are differentially a...
Autores principales: | Lopez-Font, Inmaculada, Lennol, Matthew P., Iborra-Lazaro, Guillermo, Zetterberg, Henrik, Blennow, Kaj, Sáez-Valero, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318932/ https://www.ncbi.nlm.nih.gov/pubmed/35886870 http://dx.doi.org/10.3390/ijms23147522 |
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