Genetically Encoded Fluorescent Sensors for SARS-CoV-2 Papain-like Protease PLpro

In the SARS-CoV-2 lifecycle, papain-like protease PLpro cuts off the non-structural proteins nsp1, nsp2, and nsp3 from a large polyprotein. This is the earliest viral enzymatic activity, which is crucial for all downstream steps. Here, we designed two genetically encoded fluorescent sensors for the...

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Detalles Bibliográficos
Autores principales: Sokolinskaya, Elena L., Putlyaeva, Lidia V., Polinovskaya, Vasilisa S., Lukyanov, Konstantin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318946/
https://www.ncbi.nlm.nih.gov/pubmed/35887174
http://dx.doi.org/10.3390/ijms23147826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318946/
https://www.ncbi.nlm.nih.gov/pubmed/35887174
http://dx.doi.org/10.3390/ijms23147826

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