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Genetically Encoded Fluorescent Sensors for SARS-CoV-2 Papain-like Protease PLpro
In the SARS-CoV-2 lifecycle, papain-like protease PLpro cuts off the non-structural proteins nsp1, nsp2, and nsp3 from a large polyprotein. This is the earliest viral enzymatic activity, which is crucial for all downstream steps. Here, we designed two genetically encoded fluorescent sensors for the...
Autores principales: | Sokolinskaya, Elena L., Putlyaeva, Lidia V., Polinovskaya, Vasilisa S., Lukyanov, Konstantin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318946/ https://www.ncbi.nlm.nih.gov/pubmed/35887174 http://dx.doi.org/10.3390/ijms23147826 |
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