Protons in Gating the Kv1.2 Channel: A Calculated Set of Protonation States in Response to Polarization/Depolarization of the Channel, with the Complete Proposed Proton Path from Voltage Sensing Domain to Gate

We have in the past proposed that proton motion constitutes the gating current in the potassium channel K(v)1.2 and is responsible for the gating mechanism. For this to happen, there must be a proton path between the voltage-sensing domain (VSD) and the channel gate, and here we present quantum calc...

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Detalles Bibliográficos
Autores principales: Kariev, Alisher M., Green, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318985/
https://www.ncbi.nlm.nih.gov/pubmed/35877921
http://dx.doi.org/10.3390/membranes12070718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318985/
https://www.ncbi.nlm.nih.gov/pubmed/35877921
http://dx.doi.org/10.3390/membranes12070718

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