Loss of Serum Glucocorticoid-Inducible Kinase 1 SGK1 Worsens Malabsorption and Diarrhea in Microvillus Inclusion Disease (MVID)

Microvillus inclusion disease (MVID), a lethal congenital diarrheal disease, results from loss of function mutations in the apical actin motor myosin VB (MYO5B). How loss of MYO5B leads to both malabsorption and fluid secretion is not well understood. Serum glucocorticoid-inducible kinase 1 (SGK1) r...

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Detalles Bibliográficos
Autores principales: Ahsan, Md Kaimul, dos Reis, Diego Carlos, Barbieri, Andrea, Sumigray, Kaelyn D., Nottoli, Timothy, Salas, Pedro J., Ameen, Nadia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319011/
https://www.ncbi.nlm.nih.gov/pubmed/35887942
http://dx.doi.org/10.3390/jcm11144179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319011/
https://www.ncbi.nlm.nih.gov/pubmed/35887942
http://dx.doi.org/10.3390/jcm11144179

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