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Identification of Recurrent Chromosome Breaks Underlying Structural Rearrangements in Mammary Cancer Cell Lines

Cancer genomes are characterized by the accumulation of small-scale somatic mutations as well as large-scale chromosomal deletions, amplifications, and complex structural rearrangements. This characteristic is at least partially dependent on the ability of cancer cells to undergo recurrent chromosom...

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Detalles Bibliográficos
Autores principales: Senter, Natalie C., McCulley, Andrew, Kuznetsov, Vladimir A., Feng, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319013/
https://www.ncbi.nlm.nih.gov/pubmed/35886011
http://dx.doi.org/10.3390/genes13071228