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Levetiracetam Suppresses the Infiltration of Neutrophils and Monocytes and Downregulates Many Inflammatory Cytokines during Epileptogenesis in Pilocarpine-Induced Status Epilepticus Mice

Acute brain inflammation after status epilepticus (SE) is involved in blood–brain barrier (BBB) dysfunction and brain edema, which cause the development of post-SE symptomatic epilepsy. Using pilocarpine-induced SE mice, we previously reported that treatment with levetiracetam (LEV) after SE suppres...

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Detalles Bibliográficos
Autores principales: Matsuo, Taira, Komori, Rie, Nakatani, Minami, Ochi, Shiori, Yokota-Nakatsuma, Aya, Matsumoto, Junichi, Takata, Fuyuko, Dohgu, Shinya, Ishihara, Yasuhiro, Itoh, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319101/
https://www.ncbi.nlm.nih.gov/pubmed/35887020
http://dx.doi.org/10.3390/ijms23147671