Long-Term Treatment with Bortezomib Induces Specific Methylation Changes in Differentiated Neuronal Cells

SIMPLE SUMMARY: We exposed LUHMES cells, differentiated into mature neurons, to bortezomib (BTZ) in two treatment cycles and analyzed the methylomes of these cells after each cycle, controlling the analysis for the methylation changes potentially induced by the long-term culture. Our results show th...

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Detalles Bibliográficos
Autores principales: Łuczkowska, Karolina, Taryma-Leśniak, Olga, Bińkowski, Jan, Sokołowska, Katarzyna E., Strapagiel, Dominik, Jarczak, Justyna, Paczkowska, Edyta, Machaliński, Bogusław, Wojdacz, Tomasz K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319119/
https://www.ncbi.nlm.nih.gov/pubmed/35884461
http://dx.doi.org/10.3390/cancers14143402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319119/
https://www.ncbi.nlm.nih.gov/pubmed/35884461
http://dx.doi.org/10.3390/cancers14143402

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